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结直肠癌(colorectal cancer,CRC)是人类常见的恶性肿瘤之一。在西方发达国家其发病率居恶性肿瘤的第二位。随着社会经济的快速发展,居民生活方式、饮食结构的西方化和环境的改变,近年我国CRC的发病率呈持续上升趋势,已跃居第3～5位。统计学预测表明,在不久的将来CRC发病率将超过胃癌,成为胃肠道肿瘤中导致患者死亡的主要原因。因此,对CRC的发生、发展及治疗、预防的深入研究具有重要意义。现将2012年美国消化疾病周(DDW)会议中有关结直肠癌的研究新进展总结于下。
Colorectal cancer (colorectal cancer, CRC) is one of the common human malignant tumors. In western developed countries, the incidence of malignant tumors ranks second. With the rapid socio-economic development, the lifestyle of residents, the westernization of the diet and the change of the environment, the incidence of CRC in China has been on a rising trend in recent years and has risen to No. 3 to No. 5. Statistical predictions indicate that the incidence of CRC will surpass that of gastric cancer in the near future and become the leading cause of death in patients with gastrointestinal tumors. Therefore, the occurrence, development and treatment of CRC, in-depth study of prevention is of great significance. The 2012 Progress of Digestive Disease Week (DDW) Conferences on colorectal cancer are summarized below.