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类风湿性关节炎是一种病因尚未阐明的慢性全身性免疫性疾病。其主要临床表现为慢性、多滑膜、对称性关节炎及关节外病变,且病情逐渐加重,如果治疗不当或不及时,可造成残疾。因此,早期诊断和治疗类风湿性关节炎对改善患者的预后具有重要意义[1]。类风湿因子(RF)是临床上最早用于检测类风湿性关节炎的指标,但其特异性较低。近年来发现抗环瓜氨酸肽(CCP)抗体在类风湿性关节炎的诊断中有高度的特异性[2]。本文旨在研究联合检测抗CCP
Rheumatoid arthritis is a chronic, systemic immune disease whose etiology has not yet been elucidated. The main clinical manifestations of chronic, synovial, synovial symmetry, and extra-articular lesions, and the condition gradually aggravated, if not treated properly or not, can cause disability. Therefore, early diagnosis and treatment of rheumatoid arthritis to improve the prognosis of patients with great significance [1]. Rheumatoid factor (RF) is the earliest clinically used to detect rheumatoid arthritis indicators, but its specificity is low. In recent years, anti-cyclic citrullinated peptide (CCP) antibodies have been found to be highly specific in the diagnosis of rheumatoid arthritis [2]. This article aims to study the combined detection of anti-CCP