目的对放疗后鼻咽部仍有残留病灶的鼻咽癌患者行鼻内镜引导下放射性125I粒子植入术的临床应用进行评估。方法鼻内镜引导下予32例放疗后鼻咽部仍有残留病灶的鼻咽癌患者行125I粒子植入术。结果全组完全缓解10例,部分缓解18例,总有效率为87.6%。5年生存率为68.8%。未出现严重并发症。结论鼻内镜引导下放射性125I粒子植入术对鼻咽癌放疗后鼻咽部残留病灶有较好的疗效,且并发症少。 Objective To evaluate the clinical application of endoscopic nasopharyngeal 125I radioactive seed implantation in patients with nasopharyngeal carcinoma after radiotherapy. Methods Thirty-two patients with nasopharyngeal carcinoma who underwent nasal endoscopy underwent radiofrequency 125I with nasal pharyngeal residual disease after radiotherapy. Results The whole group of complete remission in 10 cases, partial remission in 18 cases, the total effective rate was 87.6%. The 5-year survival rate was 68.8%. No serious complications occurred. Conclusion Nasal endoscopic guided radioactive seed 125I implantation for nasopharyngeal carcinoma after nasopharyngeal residual radiation therapy has a good effect, and fewer complications.