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的探讨脑梗死患者急性期脑脊液ＬＤＨ同功酶活性变化及其临床意义。方法脑梗死急性期患者３１例，对照组１８例，以琼脂糖凝胶电泳法检测脑脊液ＬＤＨ同功酶。结果脑梗死组与对照组比较ＬＤＨ１同功酶升高有显著差异（Ｐ＜００１），皮层动脉梗死组与腔隙性梗死组比较ＬＤＨ１同功酶升高有显著性差异（Ｐ＜００１），腔隙性梗死组与对照组比较ＬＤＨ１同功酶升高有显著差异（Ｐ＜００１）。结论脑梗死急性期脑脊液ＬＤＨ１同功酶活性增高，并与梗死体积大小、部位有关，对早期诊断及预后判断有重要价值。
To investigate the changes of cerebrospinal fluid LDH isoenzyme activity in patients with acute cerebral infarction and its clinical significance. Methods Thirty-one patients with acute cerebral infarction and 18 patients in control group were tested for cerebrospinal fluid LDH isoenzyme by agarose gel electrophoresis. Results Compared with the control group, there was a significant difference in LDH1 isoenzymes (P <001). There was a significant difference in LDH1 isoenzymes between the cerebral infarction group and the lacunar infarction group (P <0. 01) 01), lacunar infarction group compared with the control group increased LDH1 isoenzyme significant difference (P <0 01). Conclusions Cerebrospinal fluid LDH1 isoenzyme activity increases in acute stage of cerebral infarction and is related to the size and location of infarct volume. It has important value in early diagnosis and prognosis.