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光毒反应是光敏中最常见的一种副反应.严重的光毒反应及其慢性改变对人体健康危害甚大.临床报道引起光毒反应的物质——光毒剂日益增多,光毒反应检测的实验模型研究已引起人们的重视.本文着重概述光毒反应的临床表现、分子机理以及其检测模型的应用等研究进展.光毒反应化学剂、药物或植物等物质与光相互作用引起皮肤的有害反应称为光敏反应.30年代末,Epstein在进行药物引起光敏反应的对
Phototoxic reaction is one of the most common side effects of photosensitization.Perfect phototoxic reaction and its chronic changes are harmful to human health.Clinical reports of phototoxic reactions caused by substances - the increasing number of phototoxic agents, phototoxic reaction test The research of model has drawn people’s attention.This paper mainly summarizes the research progress of the clinical manifestation, molecular mechanism and the application of the detection model of phototoxic reaction.Phototoxic reaction Chemical agents, drugs or plants and other substances interact with light and cause harmful skin reactions Known as the photoreaction. In the late 1930s, Epstein was conducting a drug-sensitized pair