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目的探索血尿酸水平与缺血性脑卒中5年内复发脑梗死之间的关系。方法搜集临床资料完整的缺血性脑卒中患者160例,按照血尿酸水平不同分为正常尿酸组(114例)和高尿酸组(46例)。使用前瞻性随访的方法对患者进行随访5年调查,统计患者5年内脑梗死复发的相关资料,并进行分析。结果 5年共有34例患者复发脑梗死,其中高尿酸组19例,复发率41.3%,正常尿酸组15例,复发率13.2%,组间比较差异有统计学意义(P<0.05)。结论血尿酸水平与缺血性脑卒中5年内复发脑梗死有着明显的关联性,因此必须采取针对性的措施来降低脑梗死复发率。
Objective To explore the relationship between serum uric acid level and recurrent cerebral infarction within 5 years after ischemic stroke. Methods Clinical data of 160 patients with complete ischemic stroke were collected and divided into normal uric acid group (n = 114) and high uric acid group (n = 46) according to the level of serum uric acid. The patients were followed up for 5 years by prospective follow-up. The related data of patients with recurrent cerebral infarction within 5 years were analyzed and analyzed. Results In the 5 years, there were 34 patients with recurrent cerebral infarction. Among them, 19 patients had hyperuricemia, the recurrence rate was 41.3%, and 15 patients were normal uric acid. The recurrence rate was 13.2%. There was significant difference between the two groups (P <0.05). Conclusion There is a clear correlation between serum uric acid level and recurrent cerebral infarction within 5 years after ischemic stroke. Therefore, specific measures must be taken to reduce the recurrence rate of cerebral infarction.