人类巨细胞病毒(HCMV)为DNA病毒,是广泛感染人类的重要病原之一,尤其是胎儿、新生儿、器官移植者和免疫缺陷者感染HCMV可致严重疾患,甚至是死亡的直接原因。由于HCMV感染的诊断手段目前主要依赖血清特异性抗体的测定和病毒分离,而前者可有交叉反应的干扰,后者费时颇长,常需4周左右,致使临床医生对HCMV感染的诊断存 Human cytomegalovirus (HCMV), a DNA virus, is one of the most important pathogens widely infected in human beings. In particular, HCMV can cause severe illness and even death directly due to infection with HCMV in fetuses, newborns, organ transplant recipients and immunodeficient people. Since the diagnostic tools for HCMV infection are mainly based on the determination of serum-specific antibodies and virus isolation, the former may have cross-reaction interference, which takes a long time and often takes about 4 weeks, resulting in the clinician’s diagnosis of HCMV infection