银杏酸(ginkgolic acids)是6-烷(烯)基水杨酸衍生物,具有多种生物活性,存在于银杏的叶、果和外种皮中;类似的化合物亦存在于槚如树的果实中。作者对近年来这类化合物的结构修饰及其衍生物的生物活性进行综述,介绍几种修饰途径,并将新合成的物质与银杏酸比较活性,结果显示有良好的效果,旨在为今后银杏酸的进一步开发利用提供参考。 Ginkgolic acids are 6-alk(en)ylsalicylic acid derivatives, which have various biological activities and are found in the leaves, fruits and outer seed coats of Ginkgo biloba; similar compounds are also found in the fruits of Cinnamomum arborescens. in. The author reviewed the structural modifications of these compounds and their biological activities in recent years, introduced several modifications, and compared the newly synthesized substances with ginkgolic acids. The results showed good results, aiming at ginkgo in the future. Further development of the use of acid to provide reference.