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已知ABO血型抗原非分泌者对各种细菌或真菌感染的危险性增高,也容易发生十二指肠溃疡。本文旨在验证非分泌者发生胃十二指肠疾病的危险性增高是由于幽门螺旋菌(HP)感染易感性增高所引起的假设。病人和方法:检测106例因消化不良症状而接受内镜检查的患者血液中Lewis抗原。非分泌者仅表达Lewis A抗原,分泌者可表达Lewis B抗原。内镜下取胃窦部粘膜作尿素酶试验和Giemsa染色检测HP。结果:5例Lewis A和B抗原均阴性,不能作进一
It is known that non-secretagogues of ABO blood group antigens are at increased risk of various bacterial or fungal infections and are also prone to duodenal ulcers. This article aims to verify that the increased risk of gastroduodenal disease in non-secretors is due to the hypothesis of an increased susceptibility to Helicobacter pylori (HP) infection. PATIENTS AND METHODS: Lewis antigens were detected in the blood of 106 patients undergoing endoscopy due to dyspeptic symptoms. Non-secretors only express Lewis A antigen, secretors can express Lewis B antigen. Endoscopic sinusoidal mucosa taken for urease test and Giemsa staining HP. Results: All 5 Lewis A and B antigens were negative and could not be taken as one