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自1986年以来,从重组基因分离出5种集落刺激因子(CSF)供临床研究应用,已引起医师们的极大兴趣。CSF是一类低分子量的糖蛋白。是造血系统前期细胞的生成、增殖和分化不可缺少的刺激因子。本院自1993年10月～1994年3月底半年内,用Gran(G-CSF)在内儿科及妇科治疗血液系统肿瘤及实体瘤化疗后所致的白细胞和中性粒细胞减少者共20例,取得较好的疗效,总有效率为85%,现报道如下。
Since 1986, five kinds of colony stimulating factors (CSFs) isolated from recombinant genes for clinical research have attracted great interest from physicians. CSF is a class of low molecular weight glycoproteins. Is the hematopoietic system of pre-generation cells, proliferation and differentiation indispensable stimulus. Our hospital from October 1993 to the end of March 1994 within six months, including Gran (G-CSF), including pediatric and gynecological treatment of hematological malignancies and solid tumors of leukopenia and neutropenia caused by a total of 20 patients , Achieved better curative effect, the total efficiency of 85%, are reported below.