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目的:观察特比萘芬(兰美抒)外用联合中药外洗浸泡治疗角化型足癣的临床疗效。方法:将79例患者随机分为治疗组40例,采用中药外洗浸泡及外用特比萘芬治疗;对照组39例,仅外用特比萘芬治疗。疗程2周,观察2组患者的临床疗效和真菌学疗效,并对痊愈患者进行3月随访。结果:治疗组愈显率92.5%,优于对照组71.8%(P<0.05)。随访3月,治疗组复发率11.8%,明显低于对照组36.0%(P<0.05)。结论:中西医结合治疗角化型足癣的临床效果好,且具有良好的安全性。
Objective: To observe the clinical efficacy of terbinafine (Lan Mei Shu) topical combined with traditional Chinese medicine washing soak treatment of keratosis type athlete’s foot. Methods: A total of 79 patients were randomly divided into treatment group (n = 40), external Chinese medicine soaking and topical treatment with terbinafine, and control group (n = 39) only treated with terbinafine. The course of treatment was 2 weeks. The clinical efficacy and mycological efficacy of the two groups were observed. The patients were followed up for 3 months. Results: The cure rate was 92.5% in the treatment group, which was better than 71.8% in the control group (P <0.05). Followed up in March, the recurrence rate was 11.8% in the treatment group, which was significantly lower than 36.0% in the control group (P <0.05). Conclusion: The clinical effect of combination of traditional Chinese and western medicine on keratinized tinea pedis is good and has good safety.