C蛋白或S蛋白缺乏均与血栓形成有关.为观察在静脉性疾病及发生常与深静脉血栓形成有关的腿部溃疡患者中是否伴这些蛋白的部分或完全缺乏,作者对30例患者进行了这些蛋白血浆水平的测定.患者被分为3个临床组:(1)19例脂肪皮肤硬化(lipodermatosclerosis)伴小腿静脉性疡溃;(2)6例脂肪皮肤硬化不伴溃疡;(3)5例动脉性溃疡.凡伴发静脉性溃疡者溃疡均位于脂肪皮肤硬化区内.应用Bertina等和Comp等的方法作C蛋白功能性试验;应用Laurell火箭技术进行C蛋白免疫学试验;应用火箭技术检测游离S蛋白.结果与健康献血者所测结果(两种C蛋白检 Thrombosis was associated with a lack of either protein C or protein S. In order to observe whether there is a partial or complete absence of these proteins in venous diseases and in patients with leg ulcers often associated with deep venous thrombosis, the authors performed 30 patients The plasma levels of these proteins were measured and the patients were divided into three clinical groups: (1) 19 cases of lipodermatosclerosis with leg vein ulceration; (2) 6 cases of fatty skin sclerosis without ulcer; (3) 5 Cases of arterial ulcers .All patients with venous ulcers are located in the fatty skin sclerosis.Application Bertina et al Comp and other methods for protein C functional test; application of Laurell rocket C protein immunology experiments; the use of rocket technology Detection of free S protein Results and healthy blood test results (two C protein test