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目的观察并评价三种治疗方案对重度外阴阴道假丝酵母菌病(VVC)的疗效。方法对95例重度VVC病患者应用有效地3月巩固。治疗第1月结束时,治疗第3月结束时进行假丝酵母菌涂片检查。结果治疗1个月,3个月结束时症状,体征评分都比初诊时有明显好转(P<0·0001),治疗1个月结束时假丝酵母菌涂片转阴率为85·26%(81/95),治疗3个月结束时假丝酵母菌涂片转阴率为75·79%(72/95)。结论三种方法均可有效治疗重度VVC,关键是要巩固用药。
Objective To observe and evaluate the curative effect of three kinds of treatment on severe vulvovaginal candidiasis (VVC). Methods The application of 95 cases of severe VVC patients effectively consolidate in March. At the end of the first month of treatment, Candida smear tests were performed at the end of the third month of treatment. Results The scores of symptoms and signs at 1 month and 3 months after treatment were all significantly improved (P <0 · 0001) compared with that at first visit. The negative rate of candida smear after 1 month of treatment was 85.26% (81/95). The negative conversion rate of Candida smear was 75.79% (72/95) at the end of 3 months of treatment. Conclusion All three methods can effectively treat severe VVC, the key is to consolidate the medication.