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目的：观察庚型肝炎（ Ｈ Ｇ）临床、生化和病理特点。方法：用逆转录聚合酶链反应（ Ｒ Ｔ Ｐ Ｃ Ｒ）检测血清 Ｈ Ｇ Ｖ Ｒ Ｎ Ａ，并对２２ 例 Ｈ Ｇ的临床表现、肝功能检查和７ 例肝组织的病理特征进行分析。结果：（１） Ｈ Ｇ 的传播以输血及血制品和注射途径为主；（２）７ 例单纯 Ｈ Ｇ 的临床表现有一定隐匿性，血清丙氨酸转氨酶（ Ａ Ｌ Ｔ）、总胆红素（ Ｔｂｉｌ）、白蛋白（ Ａ）、 Ａ／ Ｇ、和凝血酶原活动度（ Ｐ Ｔ Ａ）的异常程度均明显轻于 Ｈ Ｇ重叠慢丙肝（９ 例）或慢乙肝者（６ 例）（ Ｐ＜ ０．０５）；（３）肝组织学示３ 例单纯 Ｈ Ｇ者呈急性轻型肝炎改变，而４ 例 Ｈ Ｇ 合并慢丙肝或慢乙肝者的肝组织则呈现不同程度的炎症活动和肝纤维化。结论：单纯 Ｈ Ｇ Ｖ 感染的临床症状和肝损害均较轻、预后良好，而 Ｈ Ｇ重叠慢性乙肝或慢性丙肝者则肝功能损害可较明显。
Objective: To observe the clinical, biochemical and pathological features of hepatitis G (HG). Methods: Serum H G V R N A was detected by reverse transcription-polymerase chain reaction (RT-PCR). The clinical manifestations, liver function tests and histopathological features of 22 HG patients were analyzed. Results: (1) The transmission of H G was mainly transfusion and blood products and injection route. (2) The clinical manifestations of HG in seven patients were obscure. Serum alanine aminotransferase (ALT), total bilirubin The abnormalities of Tbil, albumin (A), A / G, and prothrombin activity (P T A) were significantly lower than those of H G overlapping chronic hepatitis C (9 patients) or chronic hepatitis B patients (6 patients) (P <0.05). (3) Liver histology showed that three patients with HG showed acute hepatitis, while four patients with HG complicated with chronic hepatitis B or chronic hepatitis B showed varying degrees of inflammatory activity Liver Fibrosis. Conclusions: The clinical symptoms and liver damage of pure HGV infection are mild and the prognosis is good, while those with HG overlap chronic hepatitis B or chronic hepatitis C may have more obvious liver dysfunction.