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目的 探讨α catenin与人肺腺癌分化及转移的关系。方法 采用免疫组化染色法 ,半定量分析。结果 低分化肺腺癌组织α catenin的表达明显低于高分化组。原发癌与淋巴结转移癌表达方式多表现为一致性 ,但原发癌的表达与转移无关。结论 α catenin的表达与肺腺癌细胞分化程度密切相关 ,与转移无关。
Objective To investigate the relationship between α catenin and differentiation and metastasis of human lung adenocarcinoma. Methods Immunohistochemical staining, semi-quantitative analysis. Results The expression of α catenin in poorly differentiated lung adenocarcinoma was significantly lower than that in well differentiated lung adenocarcinoma. Primary cancer and lymph node metastasis expression of multi-performance was consistent, but the primary cancer expression has nothing to do with the transfer. Conclusion The expression of α catenin is closely related to the differentiation degree of lung adenocarcinoma cells and has nothing to do with the metastasis.