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目的探讨正常眼压性青光眼患者及正常人双眼眼压波动趋势是否一致,以指导临床抗青光眼药物的使用。方法以Goldmann压平眼压计测量11名正常眼压性青光眼和19名正常人的日眼压波动情况,测量5点,7点,10点,14点,18点,22点的双眼眼压。利用SPSS10.0软件的广义线性模型中的RepeatedMeasures过程进行分析。结果正常眼压性青光眼患者及正常人双眼眼压波动趋势存在显著统计学差异。结论正常眼压性青光眼患者及正常人双眼眼压波动趋势并不完全相同,在科研及临床工作中应将双眼区别对待。
Objective To investigate whether ocular tension fluctuation in patients with normal tension glaucoma and normal eyes is consistent to guide the clinical use of anti-glaucoma drugs. Methods The intraocular pressure fluctuations of 11 normal-tension glaucoma and 19 normal subjects were measured by Goldmann flattening tonometer. The intraocular pressure at 5, 7, 10, 14, 18 and 22 were measured . The SPSS10.0 software using the generalized linear model RepeatedMeasures process analysis. Results There was a significant statistical difference in the intraocular pressure (IOP) fluctuation between patients with normal tension glaucoma and normal subjects. Conclusions The trends of intraocular pressure fluctuation in patients with normal tension glaucoma and normal persons are not exactly the same, and should be treated differently in research and clinical work.