线粒体DNA突变与生物衰老以及老年退行性疾病的发生、发展均密切相关,阐明线粒体DNA突变的规律及其与衰老及老年退行性疾病的关系将为预防和诊治这些疾病提供分子水平的理论依据,并将在提高人类生命质量、延缓人类衰老的进程中起重要作用。 Mitochondrial DNA mutations are closely related to the occurrence and development of biological aging and senile degenerative diseases. The elucidation of the regularity of mitochondrial DNA mutations and their relationship with aging and senile degenerative diseases will provide molecular evidence for the prevention and treatment of these diseases. And will play an important role in improving the quality of human life and delaying the process of human aging.