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目的分析二甲双胍在妊娠期糖尿病中的临床价值。方法选择我院46例妊娠期糖尿病产妇并随机分组。胰岛素组采用胰岛素进行治疗,二甲双胍组则应用二甲双胍。比较两组妊娠期糖尿病治疗效果;血糖达到正常范围时间;干预前后产妇血糖、胰岛素指标;黄疸、巨大儿等不良事件发生率。结果二甲双胍组妊娠期糖尿病治疗效果高于胰岛素组,P<0.05;二甲双胍组血糖达到正常范围时间短于胰岛素组,P<0.05;出院时二甲双胍组血糖、胰岛素指标优于胰岛素组,P<0.05。二甲双胍组黄疸、巨大儿等不良事件发生率低于胰岛素组,P<0.05。结论二甲双胍在妊娠期糖尿病中的临床价值高,可有效改善母婴结局,减少并发症,值得推广。
Objective To analyze the clinical value of metformin in gestational diabetes mellitus. Methods 46 cases of gestational diabetes mellitus in our hospital were randomly divided into groups. The insulin group was treated with insulin and the metformin group with metformin. The treatment effect of gestational diabetes mellitus was compared between the two groups; the blood glucose reached the normal range; the maternal blood glucose and insulin index before and after the intervention; the incidence of jaundice, macrosomia and other adverse events. Results Metformin group gestational diabetes mellitus treatment effect was higher than that of insulin group, P <0.05; metformin group blood glucose reach the normal range of time shorter than insulin group, P <0.05; metformin discharge blood glucose and insulin indicators than insulin group, P <0.05. Metformin group jaundice, macrosomia and other adverse events were lower than the insulin group, P <0.05. Conclusion Metformin has high clinical value in gestational diabetes mellitus, which can effectively improve maternal and infant outcomes and reduce complications and is worth promoting.