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生长抑素是具有广泛抑制作用的消化道激素，它对消化道内分泌肿瘤的影响已被公认，对非内分泌恶性肿瘤的作用研究也日益增多，而且目前已用于临床试验[1～2]。但生长抑素对胆管癌细胞生长影响的研究则鲜有报道。本文研究了生长抑素一14（Somatostatin－14，SS－14）和其衍生物O
Somatostatin is a gastrointestinal hormone with a wide range of inhibitory effects. It has been recognized for its effect on endocrine tumors of the digestive tract. The role of non-endocrine malignancies has also increased, and it has been used in clinical trials [1–2]. However, studies on the effects of somatostatin on the growth of cholangiocarcinoma cells have rarely been reported. This paper studied somatostatin-14 (SS-14) and its derivatives O