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目的:探讨布地奈德联合孟鲁司特钠治疗儿童哮喘的临床效果。方法:收治小儿哮喘患儿100例,随机分成观察组和对照组各50例,对照组给予吸氧、消炎、平喘等常规治疗,同时雾化吸入布地奈德混悬液,20 min/次,2次/d,观察组在对照组的基础上于睡前口服孟鲁司特钠,治疗剂量:<5岁用量4 mg/d,>5岁用量5 mg/d。两组均连续治疗7 d。结果:两组患者气促、喘息、咳嗽、心率加快、肺部有哮鸣音及湿性啰音等症状及PEF测定值比较,差异有统计学意义(P<0.05),经过治疗,观察组总有效率98.0%,对照组总有效率84.0%,两组比较,差异有统计学意义(P<0.05)。结论:孟鲁司特钠联合布地奈德治疗小儿哮喘恢复快,疗效好。
Objective: To investigate the clinical efficacy of budesonide combined with montelukast sodium in the treatment of childhood asthma. Methods: One hundred children with asthma were randomly divided into observation group (50 cases) and control group (50 cases). The control group was given conventional therapy such as inhalation of oxygen, anti-inflammatory and asthma. At the same time, budesonide suspension was inhaled by atomization for 20 minutes , 2 times / d. The observation group took montelukast sodium orally at bedtime on the basis of the control group. The therapeutic dose was 4 mg / d at <5 years and 5 mg / d at> 5 years. Two groups were treated for 7 days. Results: There were significant differences between the two groups in symptoms of shortness of breath, wheezing, cough, heart rate, wheezing and wet rales in lungs and PEF values (P <0.05). After treatment, the total observation group The effective rate was 98.0% in the control group and 84.0% in the control group. There was significant difference between the two groups (P <0.05). Conclusion: Montelukast combined with budesonide in children with asthma faster recovery, good effect.