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本文采用单因素及ＣＯＸ多元回归分析了５９例急性白血病自身骨髓移植（ＡＢＭＴ）影响疗效的多种因素。结果表明，当采用单因素分析时发现移植时年龄＜４０岁与≥４０岁组，完全缓解（ＣＲ）至移植时间＜６月≥６组对缓解期无明显影响（Ｐ＞０．０５），ＣＲ１后移植者缓解期长于ＣＲ２后移植者，且复发率低，但两组未能得出统计学差异（Ｐ＞０．０５）。单用化疗作为预处理方案，疗效优于化疗合用放疗者（Ｐ＜０．０５）。当采用多因素分析时，则发现移植后中性粒细胞恢复所需时间及预处理方案对缓解时间有显著影响（Ｐ＜０．０５），单次移植后复发概率明显高于双次移植者。认为影响ＡＢＭＴ疗效的因素复杂，尚难得出肯定结论。
In this paper, a single factor and COX multiple regression analysis of 59 cases of acute leukemia autologous bone marrow transplantation (ABMT) affect the efficacy of a variety of factors. The results showed that there was no significant effect on the remission (P> 0.05) between the group of complete remission (CR) and the group of> After CR1 transplant recipients had longer remission than CR2 recipients, and the recurrence rate was low, but no statistical difference was found between the two groups (P> 0.05). Chemotherapy alone as a pretreatment program, the effect is better than chemotherapy combined radiotherapy (P <0.05). When using multivariate analysis, we found that the time required for the recovery of neutrophils after transplantation and the pretreatment regimen had a significant effect on the remission time (P <0.05), and the recurrence probability after single transplantation was significantly higher than that of the double transplant recipients . The factors that affect the efficacy of ABMT are complex and difficult to draw a positive conclusion.