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目的研究前列地尔注射液联合银杏达莫注射液治疗糖尿病下肢血管病变患者的临床疗效。方法 70例糖尿病下肢血管病变患者随机分为两组,观察组在常规治疗的基础上应用前列地尔注射液和银杏达莫注射液治疗。对照组在常规治疗基础上仅应用前列地尔注射液治疗,两组均治疗15 d,然后比较两组治疗前后临床表现、超声检查足背动脉血流情况及血糖。结果两组治疗后临床表现较治疗前均有改善,但观察组疗效明显优于对照组(P<0.05)。结论前列地尔注射液联合银杏达莫注射液可显著改善下肢血液循环,减轻血液高凝、高黏状态,两药联合应用能够更好地治疗糖尿病下肢血管病变。
Objective To study the clinical efficacy of alprostadil injection and ginkgo dipyridamole injection in the treatment of diabetic lower extremity vascular disease. Methods Seventy patients with diabetic lower extremity vascular disease were randomly divided into two groups. The observation group was treated with alprostadil injection and gingko-damo injection on the basis of routine treatment. The control group was treated with alprostadil injection only on the basis of conventional treatment. Both groups were treated for 15 days. The clinical manifestations, blood flow of the dorsalis pedis artery and blood glucose were compared between the two groups before and after treatment. Results The clinical manifestations of both groups were improved after treatment, but the effect of the observation group was better than that of the control group (P <0.05). Conclusion Alprostadil injection combined with ginkgo biloba injection can significantly improve blood circulation in lower extremities and relieve hypercoagulability and hyperviscosity in blood. The combination of the two drugs can better treat diabetic lower extremity vascular disease.