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目的:探讨中等强度有氧运动对社区原发性高血压病患者的降压作用及其内分泌功能的影响,以进一步探讨有氧运动对原发性高血压病的康复作用。方法:随机选取2012年7月-2013年7月社区原发性高血压患者65例,患者随机分为运动组33例和对照组32例。运动组采取中等强度运动,为期7周。对照组保持原有生活习惯,不作运动训练。观察两组的动态血压、血浆内皮素及NO水平测定。结果:运动治疗7周后,运动组收缩压、舒张压(24h SBP、24hDBP)、白天平均收缩压、舒张压(dSBP、dDBP)、夜间平均收缩压、舒张压(nSBP、nDBP)均明显下降,差异有统计学意义(P<0.05)。运动前后24hHR比较,差异无统计学意义。对照组各指标运动前后比较,差异无统计学意义。运动组运动后血浆内皮素、NO水平与运动前及对照组比较,明显升高,差异有统计学意义(P<0.05)。结论:中等强度有氧训练能够有效降低血压和改善患者血浆内皮素及NO水平,对社区高血压患者康复有积极的作用,值得在老年人中推广应用。
Objective: To investigate the effect of moderate-intensity aerobic exercise on the antihypertensive effect and its endocrine function in patients with essential hypertension in community in order to further explore the effect of aerobic exercise on the recovery of essential hypertension. Methods: A total of 65 patients with essential hypertension in our hospital from July 2012 to July 2013 were randomly selected. The patients were randomly divided into exercise group (n = 33) and control group (n = 32). Exercise group to take moderate-intensity exercise for a period of 7 weeks. Control group to maintain the original habits, not exercise training. The ambulatory blood pressure, plasma endothelin and NO levels were observed in both groups. Results: After exercise for 7 weeks, systolic blood pressure, diastolic blood pressure (24h SBP, 24h DBP), mean daytime systolic blood pressure, diastolic blood pressure (dSBP, dDBP), nocturnal mean systolic pressure (nSBP, nDBP) , The difference was statistically significant (P <0.05). 24hHR before and after exercise, the difference was not statistically significant. There was no significant difference in the indexes of the control group before and after exercise. The levels of endothelin and nitric oxide in exercise group were significantly higher than those before exercise and in control group, the difference was statistically significant (P <0.05). Conclusion: Moderate-intensity aerobic training can effectively reduce blood pressure and improve plasma endothelin and nitric oxide levels in patients with community-based hypertension has a positive effect on rehabilitation, it is worth to promote the application in the elderly.