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外科应激后的内分泌反应可导致下丘脑-垂体-肾上腺(HPA)轴以及交感神经系统的激活。而细胞反应则引起一族应激性蛋白的合成,这类蛋白被称为热休克蛋白。在体内水平观察了各种应激条件下(麻醉、开腹术、出血及其术后恢复期)内分泌反应和细胞反应间的关系,雄性无病毒Wistar大鼠经2周适应期后,在乙醚麻醉下行中线剖腹术并移动其内脏。10分钟后经腔静脉穿刺抽取4ml血模似出血。此后关闭腹腔。于手术后不同的时间杀
Endocrine reactions after surgical stress can lead to activation of the hypothalamic-pituitary-adrenal (HPA) axis as well as the sympathetic nervous system. The cellular response is caused by a family of stress protein synthesis, this type of protein is called heat shock protein. The relationship between endocrine and cellular responses under various stress conditions (anesthesia, laparotomy, hemorrhage and postoperative convalescence) was observed at the in vivo level. Male Wistar rats, after two weeks’ adaptation, were treated with ether Anesthesia is performed with a midline laparotomy and its internal organs are removed. 10 minutes after the vena cava puncture 4ml blood samples bleeding. After closing the abdominal cavity. Kill at different times after surgery