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目的探讨注射用头孢哌酮钠及其复方制剂所致皮肤不良反应的处理方案。方法对应用注射用头孢哌酮钠及其复方制剂所致皮肤不良反应的120例患者的临床资料进行回顾分析。结果经治疗后,荨麻疹患者、多形性红斑疹患者、固定性药疹患者、水疱疹患者治疗总有效率分别为97.3%、95.2%、93.3%、100.0%。荨麻疹患者、多形性红斑疹患者不良反应发生率分别为2.7%、4.8%,固定性药疹患者、水疱疹患者未出现不良反应。结论注射用头孢哌酮钠及其复方制剂所致皮肤不良反应较多,需要及早控制,采取适合患者实际的具体方案,改善患者预后。
Objective To investigate the treatment of cefoperazone sodium for injection and its adverse effects on skin caused by its compound preparations. Methods The clinical data of 120 patients treated with cefoperazone sodium for injection and adverse reactions caused by the compound preparations were retrospectively analyzed. Results After treatment, the total effective rates of patients with urticaria, erythema multiforme, fixed drug eruption and herpes zoster were 97.3%, 95.2%, 93.3% and 100.0%, respectively. Urticaria patients, patients with polymorphous erythema adverse reactions were 2.7%, 4.8%, patients with drug eruption fixed, no adverse reactions in patients with water blisters. Conclusion The injection of cefoperazone sodium and its compound preparations caused by more side effects of the skin, need to be controlled as soon as possible, to take the actual specific programs for patients to improve prognosis.