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检测了45例冠状动脉粥样硬化性心脏病患者的血浆脂质过氧化物的含量，发现患者含量比正常对照组要明显增高（P＜0．0001）。单用阿斯匹林40mg／d治疗患者，4个月后，测号血浆脂质过氧化物含量明显下降（P＜0．001）。结果提示，血浆脂质过氧化物含量的增高可能是动脉粥样硬化的一个重要因素，小剂量阿斯匹林可明显抑制脂质过氧化。
The plasma lipid peroxides levels were measured in 45 patients with coronary atherosclerotic heart disease and the levels were found to be significantly higher in the patients than in the normal controls (P <0.0001). Patients treated with aspirin 40 mg / d alone had a significant reduction in plasma lipid peroxidation after 4 months (P <0.001). The results suggest that increased plasma lipid peroxidation may be an important factor in atherosclerosis, low-dose aspirin can significantly inhibit lipid peroxidation.