实施计划免疫接种是我国婴幼儿保健工作的重要措施,由于多种因素的影响,免疫覆盖率难以达到100%。影响常规疫苗可接受性的关键因素之一是与局部和全身不良反应相关的安全性[1],所以对此应给予重视。1　临床资料1998年11月～1999年11月在我科进行免疫接种的3419人次中,32例出现 Implementation plan Immunization is an important measure for our country’s infant and child health care. Due to many factors, the coverage of immunization is difficult to reach 100%. One of the key factors affecting the acceptability of conventional vaccines is the safety associated with local and systemic adverse reactions [1], so attention should be given to this. 1 Clinical data November 1998 ~ November 1999 in our department immunization of 3419 people, 32 cases appeared