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目的:探讨乙炔雌二醇对皮下埋植避孕术后子宫异常出血的影响。方法:160例行皮下埋植避孕术后月经功能紊乱(出血型)的妇女,随机分两组,治疗组与对照组各80例。治疗组80例,对月经期长,血量多者给予口服乙炔雌二醇(30μg,po qd),每天6片,止血后,减为25μg,po,qd服2d,每天20μg服2d,依次递减为5μg,po,qd,作为维持量,连服21d为1个疗程;对于出血量相对较少者给予乙炔雌二醇15μg,po,qd,止血后,10μg,po,qd,依次递减为5μg·d~(-1),作为维持量,连服21d为1个疗程;对照组80例,给予甲硝唑片0.2g,po,tid,安络血3mg,维生素K_4 12 mg,po,tid,共7d。结果:治疗组与对照组止血效果比较:观察组有效率92.50%,对照组有效率82.50%。结论:乙炔雌二醇治疗由皮下埋植避孕引起的月经功能紊乱(出血型),在止血效果上明显优于对照组,是一种经济、安全有效的方法。
Objective: To investigate the effect of ethinyl estradiol on abnormal uterine bleeding after subdermal implantation of contraception. Methods: A total of 160 women with menstrual dysfunction (hemorrhagic type) after subcutaneous implantation of contraceptives were randomly divided into two groups, 80 cases in each treatment group and control group. The treatment group of 80 cases of long menstrual blood volume were given oral ethinyl estradiol (30μg, po qd), 6 tablets a day, after hemostasis, reduced to 25μg, po, qd for 2d, 20μg daily for 2d, followed by As a maintenance dose, even serving 21d for a course of treatment; for relatively less bleeding were given ethinyl estradiol 15μg, po, qd, hemostasis, followed by 10μg, po, qd, followed by decreasing to 5μg · d ~ (-1) as the maintenance dose, and even served 21d as a course of treatment; control group of 80 patients were given metronidazole tablets 0.2g, po, tid, and collateral blood 3mg, vitamin K_412mg, po, tid, a total of 7d. Results: The hemostatic effect of the treatment group and the control group was 92.50% in the observation group and 82.50% in the control group. CONCLUSION: Ethinyl estradiol is an economical, safe and effective method to treat menstrual dysfunction (hemorrhagic type) caused by subcutaneous implantation of contraception, which is superior to the control group in hemostasis effect.