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头颈部癌(包括鼻咽癌) PF方案 DDP 40mg/d vd.d1～d3 或DDP 80～100mg/m~2 vd.d1 5-FU 500～600mg/m~2 vd.d1～d5 每3～4周重复 BPF方案 BLM 7mg/m~2 im.或vd.d1,d5 DDP 20mg/m~2 vd.d1～d5 5-FU 500mg/m~2 vd.d1～d5 每3周重复 CAP方案 CTX 75mg/m~2 iV.d1 ADM 50mg/m~2 iv.d1 DDP 40mg/d vd.d1～d3 每3～4周重复 PTF方案 DDP 40mg/d vd d1～d3 THP 30～40mg/m~2 iv.d1 5-FU 500mg/m~2 vd.d1～d5 每3～4周重复 说明: 1.疗效较好的药物有DDP、THP、BLM、NVB及Taxol,还常用5-Fu、CTX及MTX等,其中BLM治疗高分化鳞癌见效快、缓解率高(20～40％),但缓解期较短; 2.一般采用联合化疗,且必须与放疗相接合。对颈部转移灶巨大者,常先予新辅助化疗使肿瘤缩小,再进行放疗,即化疗为放疗准备条件。
Head and neck cancer (including nasopharyngeal carcinoma) PF regimen DDP 40 mg/d vd.d1 to d3 or DDP 80 to 100 mg/m~2 vd.d1 5-FU 500 to 600 mg/m~2 vd.d1 to d5 every 3 Repeat 4 weeks of BPF regimen BLM 7mg/m~2 im. or vd.d1, d5 DDP 20mg/m~2 vd.d1~d5 5-FU 500mg/m~2 vd.d1~d5 Repeat CAP program every 3 weeks CTX 75 mg/m~2 iV.d1 ADM 50 mg/m~2 iv.d1 DDP 40 mg/d vd.d1~d3 Repeated PTF regimen DDP 40 mg/d vd d1 to d3 THP 30 to 40 mg/m~ every 3 to 4 weeks 2 iv.d1 5-FU 500mg/m~2 vd.d1~d5 Every 3 to 4 weeks repeated: 1. Drugs with good curative effects include DDP, THP, BLM, NVB, and Taxol. Also commonly used are 5-Fu and CTX. And MTX, etc., in which BLM treatment of well-differentiated squamous cell carcinoma has a quick response and a high remission rate (20-40%), but the remission period is short; 2. In general, combination chemotherapy is used and must be combined with radiotherapy. For those with large cervical metastasis, neoadjuvant chemotherapy is often used to shrink the tumor, and then radiotherapy is performed, that is, chemotherapy is a condition for radiotherapy.