曾从茜草科植物绒毛钩藤(Uncaria tomentosa)中首次分离得到1个新的3,4-二氢-β-咔啉环系统的类单萜葡糖吲哚生物碱3,4-去氢-5(S)-5-羧基长春花碱(1)以及该植物中的主要生物碱5(S)-5-羧基长春花碱(2)。化合物1的结构除绝对构型外,从光谱分析推断为化合物2的3,4-去氢化合物,化合物2由开联番木鳖苷(3)和L-色氨酸(4)组成。本次报道了化合物1的合成及其结构测定。 A novel 3,4-dihydro-β-carboline ring system-like monoterpene glucoside alkaloid 3,4-dehydro- was first isolated from the Uncaria tomentosa plant. 5(S)-5-carboxy Vinblastine (1) and the main alkaloid 5(S)-5-carboxy Vincaroline (2) in this plant. The structure of Compound 1 is inferred from the spectroscopic analysis as a 3,4-dehydrogenated compound of Compound 2 in addition to the absolute configuration, and Compound 2 is composed of open-sacred saponin (3) and L-tryptophan (4). This report reports the synthesis and structural determination of Compound 1.