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目的提高对巨大淋巴结增生症(CD)的认识。方法收集中南大学湘雅二医院1996年1月至2008年5月27例经病理学确诊的CD患者资料,分为局灶(LCD)组和多中心(MCD)组。从临床表现、病理分型、治疗等方面进行回顾性分析和总结。结果 CD的严重程度和对治疗的反应与临床和病理学分型相关,MCD和浆细胞型往往预后较差。结论 LCD和MCD是拥有不同临床表现和预后的同一疾病的两种不同类型,其在发病机制和伴发疾病上有所差异。诊断时区分亚型是十分必要的。
Objective To improve understanding of macrophages (CD). Methods The data of CD patients diagnosed by Pathology from January 1996 to May 2008 in Xiangya Second Hospital of Central South University were collected and divided into two groups: focal (LCD) group and multi-center (MCD) group. From the clinical manifestations, pathological typing, treatment and other aspects of retrospective analysis and summary. Results The severity of CD and response to treatment were associated with clinical and pathological subtypes, with poor prognosis of MCD and plasmacytoma. Conclusion LCD and MCD are two different types of the same disease with different clinical manifestations and prognosis, which are different in the pathogenesis and concomitant diseases. It is necessary to differentiate subtypes at the time of diagnosis.