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目的了解0~12岁儿童维生素D及骨营养的状况,并探讨维生素D的含量对儿童骨营养的影响。方法儿童保健门诊2013年1月-2014年1月来我院儿保门诊健康体检695名0~12岁儿童,采用酶联免疫法进行血清25-(OH)D检测,采用定量超声技术(QUS)测定超声速度值(SOS),根据同年龄、同性别SOS标准值的百分位数划成低骨强度和正常骨强度。结果 25-(OH)D的平均浓度为(64.15±31.69nmol/L),男性与女性25-(OH)D水平差异无统计学意义(t=1.631,P>0.05);维生素D缺乏组的低骨密度发生率大于维生素D正常组,前者骨的SOS值小于后者,两者统计学具有显著差异(P<0.05)。结论维生素D缺乏会影响儿童骨营养的状况乃至骨的发育,应重视3~12岁儿童维生素D的补充,增强少年儿童的身体素质。
Objective To understand the status of vitamin D and bone nutrition in children aged 0 ~ 12 years and explore the effect of vitamin D content on bone nutrition in children. Methods Children’s health clinic From January 2013 to January 2014, 695 children aged 0-12 years old were enrolled in this study. Serum 25- (OH) D was detected by enzyme-linked immunosorbent assay (ELISA), and quantitative ultrasound (QUS) ) Measured SOS, according to the same age, same-sex percentile SOS standard value into low bone strength and normal bone strength. Results The average 25- (OH) D concentration was (64.15 ± 31.69nmol / L), there was no significant difference between male and female 25- (OH) D levels (t = 1.631, P> 0.05) The incidence of low BMD was greater than that of the normal vitamin D group. The SOS value of the former was less than the latter, and the difference was statistically significant (P <0.05). Conclusion Vitamin D deficiency can affect the status of bone nutrition in children and even the development of bone. Vitamin D supplementation should be emphasized in children aged 3 to 12 years and the physical quality of children and adolescents should be enhanced.