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目的本研究对<4个月阻塞性黄疸婴儿十二指肠内的胆红素进行光吸收值动态监测,评价光吸收值在胆道闭锁诊断中的意义。方法研究对象分为胆道闭锁患儿(biliaryatresia,BA)17例(男11例,女6例;年龄2~16周,平均5.7周)及婴儿肝炎综合征患儿(infantilehepatitissyn-drome,IHS)20例(男14例,女6例;年龄3~7周,平均5周)。37例患儿接受了Bilitec十二指肠内胆红素光吸收值的监测,观察原始光吸收值曲线图,分析、比较最高光吸收值、光吸收值≥0.14U及≥0.25U的时间百分比。结果胆道闭锁组的光吸收值明显低于婴儿肝炎综合征组。结论十二指肠内胆红素光吸收值监测可为鉴别BA与IHS提供客观依据。
Objective This study was to evaluate the light absorption value of bilirubin in the duodenum of obstructive jaundice infants <4 months and evaluate the significance of light absorption value in the diagnosis of biliary atresia. Methods The subjects were divided into biliary atresia (BA) in 17 cases (11 males and 6 females; age range from 2 to 16 weeks, average 5.7 weeks) and infantile hepatitis syndrome (IHS) Cases (14 males and 6 females; aged 3 to 7 weeks, an average of 5 weeks). Thirty-seven children underwent Bilitec duodenal bilirubin absorbance monitoring. The original absorbance curve was analyzed to compare and analyze the maximum absorbance value, the time percentage of absorbance ≥0.14 U and ≥0.25 U . Results The light absorption value of biliary atresia group was significantly lower than that of infantile hepatitis syndrome group. Conclusion Intraduodenal bilirubin absorbance monitoring can provide an objective basis for the identification of BA and IHS.