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作者观察两侧分泌性中耳炎患儿147例。年龄1～15岁,平均5岁。男83女64。均持续3个月以上。近3月来无急性中耳炎、未使用抗生素且无腺样体堵塞。双盲法令病人服红霉素或安慰剂共14天。壹个月后检查,届时如两侧中耳重新充气,列为治疗有效。随访至少1年。结果:红霉素组69例中12例;安慰剂组72例中19例治疗有效,二组间无差异。性别和年龄间亦无差异。本组观察时间较以往报道为长,达1个月,认为22%OME病人可自愈,红霉素对
The authors observed 147 cases of children with secretory otitis media on both sides. Ages 1 to 15 years old, average 5 years old. Male 83 female 64. All last 3 months or more. Nearly three months no acute otitis media, no antibiotics and no adenoid plugging. Double-blind patients were given erythromycin or placebo for 14 days. One month after the check, then as both sides of the middle ear re-inflatable, as treatment effective. Follow up for at least 1 year. Results: Erythromycin group of 69 cases in 12 cases; placebo group of 72 cases in 19 cases of treatment effective, no difference between the two groups. There is no difference between sex and age. This group observed longer than previously reported, up to 1 month, that 22% of OME patients can be self-healing, erythromycin