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在生理条件下，Ｌａ系中Ｃｅ（Ⅳ）具有催化水解断裂ＤＮＡ磷酸二酯键的功能。介绍了各种催化水解的机理。将ＤＮＡ水解切割试剂和各种载体如寡脱氧核苷酸（ＯＤＮ）杂交制得的人工脱氧核酸酶能对ＤＮＡ链的特定位点进行催化水解断裂，为人工脱氧核酸酶的分子设计提供了一种新方法。
Under physiological conditions, Ce (Ⅳ) in La system has the function of catalyzing the hydrolysis of DNA phosphodiester bond. The mechanism of various catalytic hydrolysis is introduced. Artificial deoxyribonuclease prepared by hybridization of DNA hydrolytic cleavage reagent and various carriers such as oligodeoxynucleotide (ODN) can catalyze the hydrolytic cleavage of a specific site of the DNA strand and provide a molecular design for artificial deoxyribonuclease New method