围产期缺氧和(或)缺血是缺氧缺血性脑病(ｈｙｐｏｘｉｃｉｓｃｈｅｍｉｃｅｎｃｅｐｈａｌｏｐａｔｈｙ,ＨＩＥ)的重要致病因素,而由缺氧所致的脑组织病理生理改变,除再灌注损伤的脑代谢机制外,还包括脑血流调节完整性破坏、脑内水分分布的改变及颅高压的发生。因此,探讨?.. Perinatal hypoxia and / or ischemia is an important causative factor of hypoxic ischemic encephalopathy (HIE), and hypoxia-induced changes in the pathophysiology of brain tissue, in addition to reperfusion injury in the brain metabolism In addition, including the integrity of cerebral blood flow regulation damage, changes in brain water distribution and occurrence of intracranial hypertension. So, explore?