论文部分内容阅读
目的:观察经皮冠状动脉介入治疗(PCI)术前后~(99m)Tc—MIBI心肌灌注显像的变化,筛选PCI疗效可靠的预测指标。方法:48例心肌梗死患者PCI前分别行静患/运动/硝酸甘油介入~(99m)Tc—MIBI心肌灌注显像,PCI术后1～2周复查运动和静息~(99m)Tc—MIBI心肌灌注显像,以(术后静息心肌灌注显像缺损计分-术前运动心肌灌注显像缺损计分)/术前运动灌注缺损计分作为PCI术的疗效,以(术前静息心肌灌注缺损计分-术前运动心肌灌注缺损计分)/术前运动灌注缺损计分作为术前有功能存活心肌的指标、以(术前运动心肌灌注缺损计分-术前硝酸甘油心肌灌注缺损计分)/术前运动灌注缺损计分作为潜在有功能存活心肌的指标、以(术前静息心肌灌注缺损计分-术前硝酸甘油心肌灌注缺损计分)/术前静息灌注缺损计分作为药物可改善存活心肌指标。后三者分别与PCI术后疗效作直线相关分析。筛选PCI疗效可靠的预测指标。结果:PCI后运动和静息心肌灌注显像比术前均明显改善(P<0.01)。相关分析结果表明,后三者与前者相关系数分别为:r_1=0.63.P<0.01;r_2= 0.94,P<0.0001;r_3=0.92,P<0.000 1,提示潜在有功能存活心肌与PCI疗效相关性最佳。结论:心肌梗死患者PCI前进行静息/运动/硝酸甘油介入~(99m)Tc-MIBI心肌灌注显像很有必要,潜在有功能存活心肌可作为筛选PCI患者和预测PCI疗效的可靠指标。
Objective: To observe the change of ~ (99m) Tc-MIBI myocardial perfusion imaging before and after percutaneous coronary intervention (PCI) and screen the reliable predictive value of PCI. Methods: Forty-eight patients with myocardial infarction were treated with 99mTc-MIBI myocardial perfusion imaging before PCI or static exercise / 99mTc-MIBI Myocardial perfusion imaging, (postoperative resting myocardial perfusion imaging defect - preoperative myocardial perfusion imaging defect score) / preoperative exercise perfusion defect score as a PCI effect, (preoperative rest Myocardial perfusion defect score - preoperative myocardial perfusion defect score / preoperative exercise perfusion defect score as a preoperative functional survival myocardial index (preoperative myocardial perfusion defect score - preoperative nitroglycerin myocardial perfusion Defect score) / preoperative exercise perfusion defect score as an indicator of potentially functional viable myocardium with (preoperative resting myocardial perfusion defect score - preoperative nitroglycerin myocardial perfusion defect score) / preoperative perfusion defect Scoring as a medication improves myocardial viability. The latter three were respectively analyzed with the linear correlation after PCI. Screening for reliable predictors of PCI. Results: Post-PCI exercise and resting myocardial perfusion imaging were significantly improved compared with those before operation (P <0.01). Correlation analysis showed that the correlation coefficients between the latter three and the former were r_1 = 0.63.P <0.01; r_2 = 0.94, P <0.0001; r_3 = 0.92, P <0.0001, which suggested that the potential survival myocardial function was related to the efficacy of PCI The best sex. Conclusion: It is necessary to perform PCI / 99m Tc-MIBI myocardial perfusion imaging before PCI in PCI patients. Potential survival myocardial cells can be used as a reliable index to screen PCI patients and predict PCI.