检查用两种剂量钒酸钠(0.1和0.2mg/ml,放入饮水中)处理5周的糖尿病大鼠心脏、肝脏和肾脏的功能。结果表明,两种剂量钒酸钠处理未引起血清磷酸肌酸激酶(CPK)、谷一草转氨酶(GOT)、谷一丙转氨酶(GPT)、肌酐和尿素氮浓度升高。况且,在低剂量钒酸钠处理的动物血清肌酐水平明显低于糖尿病动物。本研究结果提示,在本实验条件下,钒酸钠处理不能引起糖尿病动物心脏、肝脏和肾脏的功能损害。 The function of the heart, liver and kidneys of diabetic rats treated with two doses of sodium vanadate (0.1 and 0.2 mg / ml in drinking water) for 5 weeks was examined. The results showed that the two doses of sodium vanadate did not cause elevated levels of serum creatine kinase (CPK), glutamic oxaloacetic transaminase (GOT), glutamic-pyruvic transaminase (GPT), creatinine and urea nitrogen. Moreover, serum creatinine levels were significantly lower in animals treated with low-dose sodium vanadate than in diabetic animals. The results of this study suggest that under the experimental conditions, sodium vanadate treatment can not cause cardiac, liver and kidney dysfunction in diabetic animals.