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通过对急性运动大鼠红细胞2,3-二磷酸甘油酸、血气等指标进行测试,研究间歇性低氧暴露提高有氧代谢能力的可能机理。结果表明:HS、HT组红细胞2,3-DPG均明显升高,呈非常显著性差异(P<0.01);HS组动脉-静脉血氧饱和度差值及动脉-静脉血氧含量差值均升高,具有显著性差异;HT组动脉-静脉血氧饱和度差值及动脉-静脉血氧含量差值均明显增加,具有非常显著性差异(P<0.01)。说明:间歇性低氧暴露可通过增加红细胞2,3-DPG提高向组织释放氧气的能力;间歇性低氧暴露可提高组织对氧的利用率,通过增加组织摄取、利用氧的能力来提高有氧代谢能力。
Acute exercise rat erythrocyte 2,3-diphosphoglycerate, blood gas and other indicators to test the intermittent hypoxia exposure to improve the possible mechanism of aerobic metabolism. The results showed that the 2,3-DPG of erythrocytes in HS and HT groups were significantly increased (P <0.01), and the differences of arterial-venous oxygen saturation and arterial-venous oxygen (P <0.01). The differences of arterial-venous oxygen saturation and arterial-venous oxygen content in HT group were significantly increased (P <0.01). Intermittent hypoxic exposure increases the ability of oxygen to release to the tissues by increasing the 2,3-DPG of erythrocytes. Intermittent hypoxic exposure improves the tissue’s oxygen utilization by increasing tissue uptake and using oxygen to increase Oxygen metabolism.