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已证明趋骨性放射性药物聚积在梗塞冠状组织。研究者们试图评价~(99m) 锝-亚锡葡萄糖酸盐检查早期心肌梗塞。将放射性核素摄取同使用苏木精、碱性品红苦味酸(HBFP)显微镜检查的结果作了比较。用9只成年杂种狗作实验。经外科手术结扎在冠状动脉的前空间隔束支诱发2只狗的梗塞形成;在左冠状动脉造影之际用改良的Szamos技术诱发5只狗的梗塞形成;另两只狗作对照组。两种血管造影图所见病变互不相同。冠状动脉外科手术结扎后即刻静脉注入2毫居里~(99m)锝-葡萄糖酸盐,在2和5小时后将狗处死。非外科手术组在冠状动脉梗塞形成后3到4小时给每只狗静脉注入10毫里~(99m)锝-葡萄糖酸盐,于梗塞形成后10到19小时将
Pro-spongy radiopharmaceuticals have been shown to accumulate in infarcted crowns. The researchers tried to evaluate ~ (99m) technetium-stannous gluconate for early myocardial infarction. Radionuclide uptake was compared to the results of microscopy using hematoxylin and basic fuchsin picric acid (HBFP). Nine adult mongrel dogs were used for the experiment. The occlusion of two dogs was induced by surgical ligation in the anterior space of the coronary artery. Infarct of 5 dogs was induced by modified Szamos technique during left coronary angiography. The other two dogs served as control group. The two angiograms showed different lesions. Immediate intravenous infusion of 2 millicuries of ~ (99m) technetium-gluconate immediately after coronary surgery, and dogs were sacrificed after 2 and 5 hours. Non-surgical groups received intravenous injections of 10 millimeters to 99m Tc-gluconate into each dog 3 to 4 hours after infarction of the coronary arteries, 10 to 19 hours after infarction