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伴中央-颞区棘波儿童良性癫癎是一常见的原发性良性部分性癫癎,典型表现为在儿童期起病,以部分性发作为主,发作与睡眠有关,多数在青春期后发作自然缓解,无明显神经精神及智力缺陷。脑电图背景活动正常,在中央-中颞区可见局灶性尖棘波,尤以浅睡期明显增多。抗癫癎药治疗反应良好,多有遗传倾向,预后良好。该文重点综述了国外关于伴中央-颞区棘波儿童良性癫癎的遗传学、临床表现、脑电图特征及治疗和预后各方面研究的新进展。
With central - temporal spondylosis of children with benign epilepsy is a common primary benign partial epilepsy, the typical manifestation of onset in childhood, with partial seizures, seizures and sleep related, the majority of seizures in adolescence Natural relief, no obvious neuropsychiatric and mental retardation. EEG background activity is normal, in the central - central area visible focal spikes, especially in the shallow sleep period increased significantly. Antiepileptic drugs responded well, with more genetic predisposition, a good prognosis. This review focuses on the recent advances in the field of genetics, clinical features, electroencephalographic features, and therapeutic and prognostic aspects of benign epilepsy in children with central - temporal spikes.