本文报告1例应用PUVA试行脱敏治疗的多形性日光疹患者,在疗程结束时发生肾病综合征。从两者之间的时间关系上提示PUVA治疗有引起肾病综合征的可能性。患者为38岁的白人妇女,自10岁起患多形性日光疹。1970年接受三甲基补骨脂素和日光照射治疗有效,且无副作用,继而外用避光剂、口服β-胡萝卜素和中波紫外线照射无明显的改善。1970年及 This article reports one patient with pleomorphic daylight dementia who was tested for PUVA desensitization and developed nephrotic syndrome at the end of the course of treatment. From the time between the two prompted PUVA treatment may cause the possibility of nephrotic syndrome. The patient, a 38-year-old white woman with pleomorphic solar eruption from the age of 10, In 1970, the treatment with trimethyl psoralen and sunlight was effective and without any side effects, and then topical dark agent, oral β-carotene and UVB irradiation had no significant improvement. 1970 and