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近年来,异位妊娠的发病率有升高趋势。异位妊娠的早期诊断可明显降低该病的死亡率,有效增加保留生育功能的几率。随着对与异位妊娠相关的生化标志物,如人绒毛膜促性腺激素(hCG)、孕激素、肌酸激酶(CK)、血管内皮生长因子(VEGF)、CA125,某些细胞因子,如白细胞介素2受体(IL-2R)、IL-6和-8、肿瘤坏死因子α(TNF-α)和激活素A等的不断研究,发现其在异位妊娠早期诊断中有一定价值,其检测结果配合阴道超声等辅助检查手段,可使异位妊娠的早期诊断率明显上升。
In recent years, the incidence of ectopic pregnancy has increased. Early diagnosis of ectopic pregnancy can significantly reduce the mortality of the disease, effectively increasing the chances of retaining fertility. With the biochemical markers associated with ectopic pregnancy, such as human chorionic gonadotropin (hCG), progesterone, creatine kinase (CK), vascular endothelial growth factor (VEGF), CA125, certain cytokines such as IL-2R, IL-6 and -8, tumor necrosis factor-alpha (TNF-α) and activin A and other continuous study and found that it has some value in the early diagnosis of ectopic pregnancy, The test results with the help of vaginal ultrasound and other means of inspection, can make the early diagnosis of ectopic pregnancy increased significantly.