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目的对武汉市妊娠期糖尿病(gestational diabetes mellitus,GDM)孕妇患病情况展开流行病学调查,为降低GDM发病率提供帮助。方法回顾性分析2015年1月-12月武汉市某医院体检的200例孕妇资料,依据口服葡萄糖耐量试验(Oral glucose tolerance test,OGTT)结果分为GDM组(10例)及正常组(190例),采用Logistic回归分析法对GDM独立风险因素进行分析。结果 GDM组与正常组孕妇年龄、孕次、BMI、糖尿病家族史、巨大儿生育史、孕期运动、多囊卵巢综合征(PCOS)指标比较,差异具有统计学意义(P<0.05);Logistic回归分析结果提示,年龄、糖尿病家族史、BMI为GDM的独立危险因素(OR:1.860、3.101、5.774;95%CI:3.055~5.110、4.385~6.248、5.120~6.442,P<0.05)。结论年龄、糖尿病家族史、BMI为此次研究中影响GDM孕妇的独立危险因素,应引起临床关注。
Objective To investigate the prevalence of gestational diabetes mellitus (gestational diabetes mellitus, gestational diabetes mellitus, gestational diabetes mellitus in pregnant women in Wuhan. Methods The clinical data of 200 pregnant women from a hospital in Wuhan from January to December in 2015 were retrospectively analyzed. According to the oral glucose tolerance test (OGTT), the data were divided into GDM group (n = 10) and normal group (n = 190) ), Logistic regression analysis of GDM independent risk factors were analyzed. Results There was significant difference in the age, pregnancy time, BMI, family history of diabetes mellitus, gestational age, pregnancy movement and PCOS among GDM group and normal group (P <0.05). Logistic regression The results suggest that age, family history of diabetes, and BMI are independent risk factors for GDM (OR: 1.860, 3.101, 5.744; 95% CI: 3.055-5.110, 4.385-6.248, 5.120-6.442, P <0.05). Conclusion Age, family history of diabetes and BMI are the independent risk factors influencing GDM pregnant women in this study, which should cause clinical concern.