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对１２７例ＩｇＡ肾病（ＩｇＡＮ）患者和２５例非ＩｇＡ系膜增殖性肾炎血清进行了抗内皮细胞抗体（ＡＥＣＡ）的检测。结果表明：ＩｇＡ肾病患者和非ＩｇＡ系膜增殖性肾炎患者血清ＡＥＣＡ－ＩｇＧ较正常对照组高，而ＩｇＡＮ患者较非ＩｇＡ系膜增殖性肾炎患者ＡＥＣＡ－ＩｇＧ的水平高，Ｐ＜０．０５。ＩｇＡＮ患者的ＡＥ－ＣＡ－ＩｇＡ水平较正常对照组高。ＩｇＡＮ患者按ＡＥＣＡ水平分为阳性与阴性组，对两组硬化面积比进行比较，未见明显差异。ＩｇＡ肾病患者的ＡＥＣＡ按不同年龄分组，按尿蛋白量的不同，分组进行比较，结果各组间未发现明显差异。
Anti-endothelial cell antibody (AECA) was detected in 127 IgA nephropathy (IgAN) patients and 25 non-IgA mesangial proliferative glomerulonephritis sera. The results showed that serum AECA-IgG levels in IgA nephropathy patients and non-IgA mesangial proliferative glomerulonephritis patients were higher than those in normal controls, while those in IgAN patients were higher than those in non-IgA mesangial proliferative glomerulonephritis patients (P <0.05). The level of AE-CA-IgA in IgAN patients was higher than that in normal controls. Patients with IgAN were divided into positive and negative groups according to the AECA level. There was no significant difference between the two groups in the hardened area ratio. AECA patients with IgA nephropathy according to different age groups, according to the different amount of urine protein, group comparison, the results were not significantly different between groups.