β,β-二烷硫基-α,β-不饱和酮类化合物作为一类具多反应中心的活泼中间体在有机合成中的应用,近20年来已引人注目并进行了深入广泛的研究~[1,2].以往的研究大多是针对β,β-二甲硫基-α,β-不饱和酮类化合物1进行的,而对结构相近的β,β-1,3-亚丙二硫基-α,β-不饱和酮类化合物2的研究较少.对于1类的合成,所用碱的选择至关重要~[1].实验证明叔丁醇钠和叔丁醇钾~[3～5]在1类的合成中效果较好.前文~[6]曾以六甲基二硅氨基锂(LHMDS)为碱高 The applications of β, β-dialkylthio-α, β-unsaturated ketones as a kind of active intermediates with multiple reaction centers in organic synthesis have attracted much attention and have been extensively studied in recent 20 years ~ [1, 2] .Most previous studies were conducted on β, β-dimethylthio-α, β-unsaturated ketones 1, while the structure of similar β, β- Dithio- [alpha], [beta] -unsaturated ketones 2 are less studied.1,2 For the synthesis of class 1, the choice of base used is of crucial importance.1 The experiments show that sodium tert-butoxide and potassium tert-butoxide [ 3 ~ 5] in the synthesis of a better effect in the previous ~ [6] had lithium hexamethyldisilazide (LHMDS) as a base high