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本文采用计算机辅助褶合曲线分析法不经分离分别测定了茶苯海明原料中8-氯茶碱和苯海拉明以及片剂中8-氯茶碱与苯海拉明复盐的含量,平均回收率和变异系数分别为100.1,0.04%(8-氯茶碱)和102.4,1.34%(苯海拉明)。五批商品测定值与中国药典(1985年版)结果一致。
In this paper, computer-assisted convolution curve analysis was used to determine the content of 8-chlorophylline and diphenhydramine in the raw materials of tea benzene and the double-salt of 8-chlorophylline and diphenhydramine in the tablets without separation, The average recovery and coefficient of variation were 100.1,0.04% (8-chlorophylline) and 102.4,1.34% (diphenhydramine), respectively. The results of five batches of products are consistent with the results of the Chinese Pharmacopoeia (1985 edition).