肝干细胞（ｈｅｐａｔｉｃ ｓｔｅｍ ｃｅｌｌ）是否存在？如果存在，它们位于肝脏的何处？这些问题已激烈地争论了多年。直到最近，在对啮齿类动物模型的研究及对人类肝脏疾病发病机理的细胞生物学研究获得了确凿的证据之后，才初步平息了争论：肝干细胞确实存在；它们多数位 Is hepatic stem cell present? Where are they located in the liver? These issues have been heatedly debated for many years. Until recently, there was solid evidence of research in rodent models and in cellular biology of the pathogenesis of human liver disease that initially subsided the debate: liver stem cells do exist; their majority