一、前言自1968年Karim应用前列腺素(简称PG,下同)催产、引产以来,许多报导一致认为有效。基本前列腺素PGE_2,F_2α制剂已有商品出售,临床主要使用于催产,促进分娩,而应用于引产不广泛的原因是由于有副作用。因此希望找到副作用小、使用方便、适用于引产的PG类药物。本文介绍PG用于引产的最新进展。二、人工引产法目前日本允许妊娠24周内的孕妇进行人工引产。此时期的子宫肌对催产素无反应,如用催产素引产技术上非常困难。但前列腺 I. Introduction Since 1968 Karim prostaglandin (referred to as PG, the same below) oxytocin, since the induction of labor, many reports agreed that the effective. Basic prostaglandin PGE_2, F_2α preparations have been sold, the main clinical use of oxytocin, to promote childbirth, but not widely used for induction of labor due to side effects. So I hope to find side effects, easy to use, suitable for induction of PG drugs. This article describes the PG for the latest progress of labor. Second, the artificial induction of labor At present, Japan allows pregnant women within 24 weeks of pregnancy induced labor. Uterine muscle during this period no response to oxytocin, such as the use of oxytocin induction of labor is very difficult. But the prostate