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作者等报告11例非特异性溃疡性结肠炎伴广泛粘膜剥离。粘膜剥离均由钡剂灌肠诊断。在X线检查时,剥离粘膜处星双重阴影,范围较广泛,其长度均超过7cm。患者均经抗生素、肾上腺皮质激素和静脉内营养治疗。除4例外,所有病人均予以禁食。治疗结果2例痊愈,该2例未曾禁食。余9例均因长期内科治疗无效而手术,其中8例作全结肠切除,1例作结肠造瘘术。手术治疗时均证实患有广泛粘膜剥离。手术治疗结果,3例死亡,余痊愈。根据上述观察,作者等认为溃疡性结肠炎伴粘膜广泛剥离者,虽过去未见报道,但并非罕见,且预后严重,值得注意。对这类严重病例,可先内科治疗。在治疗4～6天后,如情况未见好转,则不论有无出血、穿孔或结肠扩张,均须立即进行全结肠切除术。作者等认为
The authors reported 11 cases of nonspecific ulcerative colitis with extensive mucosal dissection. Mucosal dissection is diagnosed by barium enema. In the X-ray examination, the mucosal stripping double shadow, a broader range of its length are more than 7cm. Patients were treated with antibiotics, corticoids and intravenous nutrition. All but four patients were fasted. Two cases of treatment results were cured, the two cases have not fasting. The remaining nine cases were ineffective due to long-term medical treatment and surgery, of which 8 cases of total colon resection, 1 case of colostomy. Surgical treatment were confirmed with extensive mucosal dissection. Surgical treatment results, 3 patients died, I recovered. Based on the above observations, the authors believe that ulcerative colitis with extensive mucosal dissection, although not previously reported, but not uncommon and the prognosis is serious and worth noting. For such serious cases, medical treatment can be. In the treatment of 4 to 6 days, if the situation has not improved, with or without bleeding, perforation or colon expansion, must be immediately carried out by the whole colon resection. The author thinks so